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July - December 2018
Volume 15 | Issue 2

This journal has been online since Saturday, April 05, 2013

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ORIGINAL ARTICLES


 
 
 

KNOWLEDGE OF SUDDEN INFANT DEATH SYNDROME AND RECOMMENDED SLEEP PRACTICES FOR INFANTS AMONGST DOCTORS AND NURSES: A MULTICENTRE STUDY IN SOKOTO, SOKOTO STATE, NIGERIA

Isezuo KO1, Adamu A, Jiya FB, Ibitoye PK, Onankpa BO, Sani UM1, Bolajoko TA, Sanni MA, Bello LA

Background: The American Academy of Paediatrics (AAP) started the Back to sleep campaign since 1992 to reduce the incidence of Sudden infant death syndrome (SIDs) and expanded its recommendations in 2011 to include provisions to ensure safe sleep environment for infants. Health workers, especially doctors and nurses are to ensure correct information is given to parents. However, knowledge gaps still exist among health workers even in developed countries.
Objective: To assess knowledge on SIDs and recommended sleep practices for infants among doctors and nurses in two major hospitals, Usmanu Danfodiyo University Teaching Hospital (UDUTH) and Specialist Hospital Sokoto (SHS) in Sokoto town in order to bridge knowledge gap among healthcare providers.
Methods: This was a cross-sectional multicentre study of 154 health workers carried out between 1st August, 2016 and 31st October, 2016. Doctors from the Paediatrics and Obstetrics departments, nurses in all the Paediatric and Obstetrics units of both hospitals were consecutively recruited. A structured questionnaire on knowledge of Sudden infant death syndrome and sleep recommendations was administered. Data was analysed with SPSS version 22
Results: Out of 154 health workers that participated, only 25 (16.2%) were aware of the AAP recommendations. Seventy-six (49.4%) selected side position as the recommended position while 62 (40.3%) selected supine position. More nurses than doctors (57.6% vs 32.3%) gave advice to mothers on sleep position even though the doctors were more aware of the AAP recommendations and correct infant sleep position. Although, the paediatric nurses had more knowledge of the recommended supine sleep position, more obstetric nurses gave advice to mothers about sleep position (p =0.005). Also, paediatricians had more knowledge of the supine sleep position (p = 0.03) compared to obstetricians.
Conclusion: More doctors and nurses in this study selected the side sleeping position as the recommended one. Also, frequency of giving advice to mothers on sleep position was also low.

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FEEDING DISORDERS IN CHILDREN ATTENDING THE NEUROLOGY CLINIC IN A TERTIARY HOSPITAL IN SOUTHERN NIGERIA.

Anthony O. Atimati, Olusola P. Okunola

Background: Feeding disorders are estimated to occur in up to 25 - 35% of healthy children and 80% of neurologically impaired children. Dysfunctional oral-motor control, abnormal neurologic maturation, poor seating posture during feeding among others result in feeding problems in children with neurologic disorders. Early detection and nutritional support are important in preventing poor growth and development which may result from feeding disorders.
Objective: To ascertain the presence of feeding disorders in children attending the neurology clinic of the University of Benin Teaching Hospital.
Materials and Method: A descriptive cross-sectional study carried out in the University of Benin Teaching Hospital. A semi-structured interviewer-administered questionnaire was used in obtaining information from the parents/caregivers of the children who were recruited consecutively from the neurology clinic.
Results: Of the 154 subjects recruited for the study 63 (41%) and 59 (38%) had cerebral palsy and seizure disorder/epilepsy respectively. Fifty-six caregivers (36.4%) had unpleasant experience during mealtimes. Excessive salivation, choking and chewing difficulties ranked highest among the feeding problems in the children. Forty-four (28.6%) children had multiple feeding problems. Gender, age group, feeding experience and neurological diagnosis were significantly associated with multiple eating problems. Forty-one (26.6%) children were underweight while 7.1% were overweight.
Conclusion: Feeding problems, which are often accompanied by unpleasant mealtime experience for caregivers, are common in children with neurological impairments. Assessment of the feeding pattern and nutritional status of children should be undertaken in the outpatient neurology clinic.

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CORRELATION BETWEEN AETIOLOGY, STAGE AND DURATION OF CHRONIC KIDNEY DISEASE AND HEARING LOSS

Adekwu A, Ibiam F A, Ogbeyi G A, Abah R, Agaba E I, Ezeanolue B C,

Background: The incidence of chronic kidney disease (CKD) in Nigeria and the Black race in general is on the increase with attendant high morbidity and mortality. Several aetiologic factors have been implicated in CKD which include hypertension, diabetes mellitus, glomerulonephritis, obstructive uropathy, recurrent pyelonephritis and adult polycystic kidney disease (ADPKD) amongst others. Whatever maybe the aetiologic factor of the CKD, there is reported effect of this condition on the auditory organ at the level of cochlea because of certain similarities.
Objective: To determine if there is any correlation between the aetiology, stage and duration of chronic kidney disease with the severity of hearing loss.
Methodology: A one-year prospective study which sought information on demographics, aetiologic factors, otologic, drug and occupational histories of patients with chronic kidney disease using a structured interviewer administered questionnaire. Additionally, body weight, height, blood pressure, fasting blood sugar and serum creatinine were measured for all the patients while pure tone audiometry(PTA) and glomerular filtration rate (GFR) were measured or calculated respectively.
Results: One hundred CKD patients were analysed, comprising of 66 males and 34 females with a male to female ratio of 1.9:4. Their ages ranged from 15years to 75years with mean age of 40.2(SD±18.4). The majority of the studied population was in the 45-54 years (28%). Sensorineural high frequency hearing loss was found in 60 patients, made up of 49 in both ears and 11 unilateral (3 and 8 in right and left ears respectively). These gave a total of 109 ears (54.5%). Chronic kidney disease resulting from chronic glomerulonephritis or hypertension accounted for 45.0% and 36.0% cases respectively. Hearing loss increases with the CKD stage accounting for 15.6%, 34.9% and 48.6% for stages 3, 4 and 5 respectively. The longer the duration of the CKD, the more depressed was the mean hearing threshold (P=0.0047; r=0.870).
Conclusion: There is significant correlation between hearing loss in the high frequencies and duration and stage of chronic kidney disease patients. Therefore, we recommend health education with a view to identifying this category of patients’ early and effecting periodic hearing assessment in them.

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ORIGINAL ARTICLES


 
 
 

SOCIOCULTURAL BELIEFS REGARDING MIDLINE DIASTEMA AMONG UNDERGRADUATE STUDENTS ATTENDING A NIGERIAN UNIVERSITY

Enabulele Joan E, Aghamiogie Ehis

Introduction: Perception of maxillary midline diastema as an aesthetic trait varies in relation to culture, age group, and racial background. This study determined the self-reported prevalence of maxillary midline diastema as well as assessed the sociocultural beliefs regarding maxillary midline diastema among undergraduate students of different ethnicity attending a Nigerian university.
Methods: A descriptive cross-sectional study of undergraduate students in University of Benin. A self-administered structured questionnaire was utilized for this study. The questionnaire sought information on socio-demographic profile of the participants, self-reported presence of midline diastema, the characteristics of the diastema and sociocultural beliefs regarding midline diastema. Statistical analysis was done using IBM SPSS 21.0. Cross tabulation was used to report categorical variables which were presented as counts and percentages. Chi-square test was applied to determine associations between variables with the level of significance set at p<0.05.
Results: A total of 400 students aged 16 to 46 years and a mean age of 21.86 years (±3.07) took part in this study. 29% of the study population had maxillary midline diastema. Most cases were recorded in the maxillary arch (96.6%). All ethnic groups and students in lower age group saw maxillary midline diastema as a sign of beauty and perceived it to be more attractive in female.
Conclusion: Based on the study, midline diastema is regarded as a sign of beauty, all ethnic groups perceived midline diastema as an aesthetic attribute.

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ORIGINAL ARTICLES


 
 
 

FACTORS ASSOCIATED WITH EARLY MORTALITY IN HIV PATIENTS THAT PRESENTED FOR CARE IN A TERTIARY HEALTH FACILITY IN NORTHEASTERN NIGERIA

Ballah Akawu Denue, Wadzani Gashau

Background: Despite huge success achieved in HIV management through early detection of cases and use of potent antiretroviral therapy (ART), human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) remains amongst the leading causes of death in sub-Saharan Africa. Aim: To identify factors associated with death within one year of initiating ART in HIV/AIDS patients that presented for care with advanced disease (in WHO clinical stages III/IV).
Methods: This study analysed the records of patients admitted with advanced HIV disease, between January 2009 and December 2013. Information needed was sourced from patients’ medical records and death certificates. During the study period, 273 patients were admitted, out of whom 119 satisfied the inclusion criteria. Of the 119 patients, 108 with complete data were analysed giving a retention rate of 90.1%. Among the participants, 51 cases died within one year of initial evaluation and 57 were alive after one year (survivors).
Results: Males were older than females in both the mortality cohort (p = 001) and survivor cohort (p = 0.01). Male gender (Crude odds ratio [COR] 2.27, 95% confidence interval [CI]: 1.08 – 5.21); HIV RNA viral load = 100,000 copies/ml (COR 2.69, 95% CI: 1.20 – 6.03) and anaemia (haemoglobin concentration < 10.5g/dl) (COR 6.66, 95%CI: 2.74 – 16.17) were predictors of mortality in univariate analysis. After adjusting for confounding variables on multivariate analysis, anaemia (Adjusted odds ratio [AOR] 4.33, 95%CI: 1.27 – 14.83) remained the only predictor of death
Conclusion: Anaemia is an independent predictor of early mortality in patients that present with advanced HIV disease in our environment.

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ASSESSMENT OF KNOWLEDGE, ATTITUDE AND PRACTICE TOWARDS HEPATITIS B VIRUS SCREENING AND VACCINATION AMONG AUXILIARY HEALTH WORKERS IN UNIVERSITY OF MAIDUGURI TEACHING HOSPITAL (UMTH)

Kida IM, Umar B, Goni BW, Garbati MA, Adamu I, Ogah D, Bakki B, Dayar AD, Ummate I, Yusuph H.

Background: Hepatitis B is one of the important blood-borne diseases that pose a challenge to public health. It is the most common cause of liver infection globally. Despite the high risk of hepatitis B in healthcare workers, the knowledge, attitude, and practice concerning hepatitis B infection among them is low.
Aim: To document the level of awareness of HBV infection among auxiliary health workers and to identify the source of information on the knowledge of auxiliary health workers towards HBV infection.
Methods: A cross-sectional descriptive study involving 240 auxiliary health workers in the University of Maiduguri Teaching Hospital that were interviewed using an interviewer-administered questionnaire.
Results: The study population comprised an equal number of males (50%) and females (50%). The mean age of the respondents was 32.9 years. Majority had secondary education 96(40%) and were Kanuri tribe. In total, 81.1% of respondents knew that HBV is caused by a virus, and 70.8% believed the virus can be transmitted through blood transfusion and 71 (29.6%) through unprotected sexual intercourse. One hundred and sixty-eight (74.2%) respondents were aware of the availability of HBV screening programmes in the facility, 131 (54.6%) of them had been screened for HBV and received HB vaccine. Majority (96.7%) of the respondents believed that HBV is a public health problem, 93.8% agree their job puts them at high risk of HBV infection.
Conclusion: The study concluded that majority of the respondents had information about HBV, and the major source of information was through other health workers. A good number of the respondents had been screened or taken vaccination against HBV.

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SOCIO-DEMOGRAPHIC AND CLINICAL PROFILE OF BREAST CANCER PATIENTS IN BENIN CITY, NIGERIA

Oludare Folajimi Adeyemi,1 Godwin Enosakhare Okungbowa,2 Osesogie Usuale Ogbeide

Background: Although breast cancer is reported as the commonest cancer in women, there is a dearth of literature and research concerning patient profile and utilization of hospital radio-therapeutic services.
Aim: The aim of the study was to document the knowledge of socio-demographic profile and clinical pattern which is a requirement for control measures and appropriate treatment of cancers.
Method: This was a retrospective study made up of 257 patients seen in University of Benin Teaching Hospital (UBTH) and undergoing their radio-therapeutic clinic visits for breast cancer. The data was analysed using Statistical Package for Social Sciences (SPSS) version 20.0.
Result and Conclusion: The age ranged between 23 - 83 years, with a mean of 48.94 ± 11.09 years, median of 48 years and mode of 43 years. Out of these total 47.6% of the breast cancers were located in the right breast and 51.2% were on the left, with invasive ductal carcinoma (93.7%) as the most common histological type. This basic information on socio-demographic and clinical profile of patients can help plan and optimize the utilization of hospital services, more especially in a resource poor country like Nigeria.

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ORIGINAL ARTICLES


 
 
 

HEAD INJURY IN MAIDUGURI: AN 18 MONTH REVIEW

Usman B, Mohammed B

Background: Traumatic brain injury is a leading cause of death and disability in young adults (?44years) and in children (>1 year). Early diagnosis, prevention of secondary injury and treatment of complications reduces the morbidity and mortality. However, with the on-going civil-military conflict in our region (Boko Haram), achieving this is difficult.
Method: A retrospective analysis of case records of all patients with traumatic brain injury managed by our unit from May 2015 to October 2016 (18 months).
Results: A total of 1529 trauma cases were recorded in the Emergency Department. There were 269 traumatic brain injuries. One hundred and forty-seven (147) were treated at the emergency department, while 122 patients were transferred to the wards and Intensive Care Unit (ICU) for further management. Road traffic accident (RTA) was the leading cause (62.87%) followed by missile injury (bomb blast/Improvised Explosive Device [IED] and Gunshot) in 65 patients (24.17%). Neuro-imaging was not readily available for assessment. Fourteen (14) had various surgical interventions. Good outcome was recorded in 239 patients (88.91%). Mortality was recorded in 50% of ICU patients.
Conclusion: In addition to RTA, missile injuries are common causes of head injury in our society ravaged by a civil-military conflict (Boko Haram). The severity of the primary injury, non-availability of functional neuroimaging to guide subsequent intervention contributed to the mortalities.

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PARAPLEGIA: AN UNCOMMON PRESENTATION OF PARASAGITTAL CONTUSIONS; A CASE SERIES

Babagana Mohammed, Nasiru Ismail Jinjiri, Mohammad R. Mahmud, Ali Lassieni

Background: In our hospital setting, the presence of a sudden bilateral lower limb paraplegia following trauma directs the mind of the clinician towards injury to the spinal cord; however, cerebral causes of paraplegia do occur even though such presentations are rare entities after traumatic brain injury. Patients presenting with acute inability to move both lower limbs were diagnosed to have spinal cord injury following multiple trauma or road traffic accident by casualty staff.
Methods: We report three cases seen over a period of two years, with the patients presenting with a history of acute paraplegia following trauma: assaults or road traffic accident. Further evaluation revealed alteration or loss of consciousness and evidence of injuries to the skull. Neurological examinations revealed flaccid weakness of the lower limbs with power of grade 0 (MRC grade: 0/5), all sensory modalities of the lower limbs were preserved. Normal anal tone and superficial abdominal reflexes; there were no areas of tenderness or deformity over the spine.
Results: Initial radiologic evaluations of the spine showed normal findings, and all patients had computed tomography (CT) of the brain that revealed acute bilateral parasagittal contusions in the fronto-parietal region. Following active physiotherapy over a period of three to seven (3-7) weeks, all patients regained muscle power of at least 4/5, ability to walk, and were later discharged from the hospital.
Conclusion: A high index of suspicion is needed in diagnosing paraplegia secondary to different aetiologies such as parasagittal contusion. A low threshold in requesting for neuroimaging scan of the brain is required, although, Computed tomography (CT) done within first 1-3 days may be falsely negative.

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archives-15-1

Written by Administrator. Posted in Archives

 
 

 

January - June 2018
Volume 15 | Issue 1

This journal has been online since Saturday, April 05, 2013

PDF access
This Journal allows immediate access to content in HTML + PDF for both current and archived editions.

Mobile access
Full text of the articles can be accessed via our android application and mobile site free of charge.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License

 

 

ORIGINAL ARTICLES


 
 
 

PHYSICAL ACTIVITY AND QUALITY OF LIFE AMONG ADULTS IN MAIDUGURI, NIGERIA

Rufa’i AA, Oyeyemi AL, Salamatu UA, Saidu IA, Aishatu US, Oyeyemi AY

Background: Engaging in sufficient physical activity (PA) improves health and quality of life (QOL) across all ages.
Objective: The objective of this study was to determine the relationship between demographic variables, PA and QOL among adults in Maiduguri, Nigeria.
Methods: A total of 390 apparently healthy male and female adults (age range =18–65 years) in Maiduguri participated in the study. PA level was assessed with the International Physical Activity Questionnaire- Short Form. Health-related QOL was assessed using the physical and mental components summary scales (PCS & MCS) of the MOS Short Form-12 health survey questionnaire. Pearson’s correlation was used to explore the relationships between age, PA and QoL of the participants.
Results: The mean age of the participants was 29.51±10.12 years. About half of the participants were males (52.8%) and employed (54.4%). Age was inversely correlated with total PA (r= -0.13, P<0.001) and PCS (r= -0.32, P<0.001). Total PA was negatively correlated with PCS (r= -0.13, P= 0.010) but positively with MCS (r= 0.17, P= 0.001). There was significant difference in total PA (P<0.001), PCS (P<0.001) and MCS (P<0.05) between female and male, and also between the employed and unemployed. Also, there was significant difference in PCS (P<0.001) and MCS (P= 0.003) between participants with higher education and those with non-formal education.
Conclusion: Significant relationships were found between demographic variables, PA and QOL components among the participants. These results affirm that PA is important to improving the QOL of adults in Maiduguri.

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PREVALENCE AND CAUSES OF OCULAR MORBIDITY AMONG PRIMARY SCHOOL CHILDREN IN SOKOTO METROPOLIS, NORTH-WESTERN, NIGERIA

Olatunji Lawal K, Oche Mansur O, Adamu Habibullah1, Mohammed Dantani A, Abdulsalam Latifatu B, Arisegi Sarafadeen A

Background: Vision plays an important role in child development, as this is essential for receiving visual sensory information from the external environment and social development.
Objectives: This study aims at determining the prevalence and causes of ocular morbidity among primary school children within sokoto metropolis.
Materials and Method: A descriptive cross sectional survey of primary school children in Sokoto metropolis was carried out between July 2016 and August 2016. Relevant socio-demographic history and ocular examination was carried out on the primary school children that were selected using a multi-stage sampling technique. Data were entered and analysed using the MS Excel 20 and Statistical Package for Social Sciences (IBM SPSS) version 20.
Results: A total of 184 pupils were surveyed; 85 (46.2%) were males and 99 (53.8%) were females. The age range was between 5 and 15 years and the mean age was10.84years ± 2.19. The prevalence of ocular morbidity among the primary school children was 29.3%. Conjunctivitis was found to be the commonest ocular morbidity with a prevalence of 17.9% followed by refractive error with a prevalence of 7.6% while no cases of colour vision or cataract were seen.
Conclusion: The sheer magnitude of ocular morbidity among primary school children calls for need to introduce or improve the school eye health program as part of the routine school heath services.

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PTERYGIUM EXCISION WITH PRIMARY CLOSURE IN SOKOTO, NORTH WEST NIGERI

Mohammed Dantani Adamu

Background: The essence of pterygium surgery is to excise the pterygium and inhibit recurrence. Multiple surgical techniques have evolved over the years to excise the pterygium and inhibit its recurrence.
Objective: To determine the outcome of pterygium excision with primary closure in terms of recurrence.
Methods: A retrospective review of medical records of all patients who had pterygium excision with primary repair during the study period at Usmanu Danfodiyo University Teaching Hospital and Specialist Hospital, Sokoto was undertaken. Data on demographic variables, extent of pterygium and pterygium recurrence after 6 months and postoperative
complications were extracted and analyzed.
Results: There were a total of 32 eyes in 32 patients studied with age range between 26 to 68 years {mean age of 47.2 (SD +12.32)}. There were 15 males and 17 females (M:F = 1:1). Majority of the patients had stage 3 pterygium (65.3%) followed by stage 2 (27.2%) and stage 4 pterygium (7.5%) was the least in frequency P=0.02, CI (2.50-2.95). There were twenty-nine patients (90.6%) with primary pterygia while three (9.4%) had recurrent pterygia. 56.2% of the patients had occupations with possible significant exposure to actinic damage. Recurrence occurred in 12.5% of the patients after 6 months’ follow-up.
Conclusion: Pterygium excision with primary closure appears to be safe and effective. Future comparative case series and randomized controlled studies are recommended

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Pattern of Cancers at a Rural Referral Centre in North-Eastern NIGERIA

 

Hadiza A. Usman, Bala M. Audu, Ibrahim M. Sanusi, Mohammed Bukar, Pindiga U. Hamidu2

Background: Cancers have wide regional, urban/rural variations in reported prevalence.
Objectives: To determine the baseline pattern of cancers in the first 5 years from Hospital-based records of cancer cases at Federal medical centre Nguru, Northeast Nigeria.
Methods: A retrospective review of all histologically confirmed cancer cases managed at a rural referral tertiary health facility in Northeast Nigeria for the period 1st January, 2009 to 31st December, 2013 was undertaken.
Results: Of the 237 histological specimens during the period under review, 165 (69.6%) were cancers. Female cancers (n=101; 61%) were more than male cancers (n=64; 39%) and the mean age (±SD) for all cancers was 48.1(±18.7) years. The mean age for cancer was lower in females (Student t-test 5.103, P < 0.001). The mean ages for the 3 commonest cancers in this centre were; 45.1 ± 15.2 years for breast; 49±10.9 years for cancer of the cervix and 67.4±7.6 years for prostate cancer. The commonest cancer sites were in the female and male genital tracts. However, review of individual cancers showed that breast cancer was the commonest (n=31; 18.8%) followed by prostate cancer (n=29; 17.6%). The 3rd commonest cancer was that of the cervix which constituted 11.5% (n=19). Skin (excluding melanoma), gastrointestinal, head and neck and melanoma constituted 8.0%, 6.6%, 6.0% and 4.2% respectively. Only 1 case of childhood cancer (endodermal sinus tumour) was seen in an 18 months old child while cancers in teenage age group (13- 19 years) constituted 3% (n=5); there were 2 squamous cell carcinoma of the skin, 1 each for Hodgkin’s lymphoma, osteosarcoma and a retinoblastoma.
Conclusion: The pattern of cancers in this rural population is similar to findings in other parts of the country. Women have the highest burden but a lower mean age of cancers in this study. Breast, prostate and cervical cancers were the 3 commonest cancers constituting 48% of the cancer burden. There is the need for strategic preventive measures, including the establishment of an oncology unit, to reduce the burden of cancers in this community.

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ORIGINAL ARTICLE


 
 

RELATIONSHIP BETWEEN GASTRIC CANCERS AND TRIO OF HELICOBACTER PYLORI INFECTION, CHRONIC GASTRITIS AND GASTRIC MUCOSAL INTESTINAL METAPLASIA AS SEEN IN JOS UNIVERSITY TEACHING HOSPITAL, NIGERIA

 
Kwaghe BV, Ochigbo AJ, Nggada HA, Emmmanuel I, Abobarin OI, Akpa PO, Richard KS
Background: In 1994 Helicobacter pylori was classified as class 1 human carcinogen by the IARC (WHO), based on epidemiological evidence. Experimental evidence was subsequently provided by Wantabe et al. This has triggered several studies on the prevalence of H. pylori in patients with Gastric cancers in various regions of the world. In Africa the infection rate in various populations as reported by some studies are not parallel to the incidence of morbidity caused by this infection.
Objective: To determine the relationship between Helicobacter pylori infection, Chronic gastritis, Gastric mucosal intestinal metaplasia with Gastric cancers.
Methodology: This was a retrospective histopathological study of all gastric cancers with adjacent non – cancerous epithelium seen between January 2005 and December 2012 in the department of Histopathology, Jos University Teaching Hospital (JUTH). Blocks and archival slides were used for the study.
Results: Out of the 79 cases of gastric cancers seen within the study period, only 46 cases had adjacent non-cancerous epithelium and were included in the study. This comprises of 38 cases of Adenocarcinoma and 8 other tumours. Chronic gastritis was seen in 33 (71.7%) cases. Intestinal metaplasia was present in 14 (30.4%), while H. pylori was seen in only 7 (15.2%) cases.
Conclusions: Gastric cancers are not rare in Jos and there is a relationship between it and the trio of H. pylori infection, chronic gastritis and gastric mucosal intestinal metaplasia.

[FULL ARTICLE (PDF)]

ORIGINAL ARTICLE


 
 

COLORECTAL POLYPS IN KANO: A TEN YEAR HISTOPATHOLOGICAL REVIEW

 

Yusuf Ibrahim, Aminu Dahiru MC

Background: Colorectal polyps are mucosal growths that occur in the large intestines. The adenomatous variants are precursors of colorectal cancer which is the third and fourth most common cancer among males and females respectively.
Objectives: This study documents the frequency, distribution and histopathological characteristic of colorectal polyps in our centre.
Method: This was a 10-year retrospective study of colorectal polyps diagnosed in the Pathology laboratory of a tertiary hospital from 2007 to 2016. Archived histopathology slides were reviewed to confirm the diagnosis. Relevant clinical information was obtained from patients' request forms. Data were presented as mean, standard deviation, frequencies and percentages. Relationships between neoplastic polyps and age, gender and anatomic site were measured using Fishers exact test.
Result: There were 124 cases of colorectal polyps recorded. Of these, were 82 (66.0%) males and 42 (34.0%) females (M:F=1.9:1). The average age at presentation was 29.0 ±23.6 years. Highest frequency of 45(36.2%) cases was in the 1st decade of life. There were 87(70.0%) cases in distal colon/rectum while 37(30.0%) were in the proximal colon. Juvenile polyps had the highest frequency overall, (60 cases, 48.0%), followed by tubular adenoma (31 cases, 25.0%), hyperplasic polyp (11 cases, 8.9%), villous adenoma (9 cases,7.3%), inflammatory polyp (6 cases,4.8%), tubulo-villous adenoma (3 cases, 2.4%), retention polyp (2 cases, 1.6%) and sessile serrated polyp (2 cases, 1.6%). There were 43 (34.7%) cases of neoplastic polyps. The average age of patients with neoplastic polyps was 47.3 years and they are located mostly in proximal colon (23/37 cases) (P<0.05).
Conclusion: Colorectal polyps are common in our environment especially juvenile polyp encountered mostly in children. We recorded significantly lower prevalence, lower mean age at presentation of neoplastic polyps compared to Western populations. This highlights the need for earlier age screening colonoscopy to detect and treat premalignant polyps.

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SONOGRAPHIC EVALUATION OF CAROTID ARTERY LUMINAL DIAMETER AND DEGREE OF STENOSIS IN ADULT DIABETIC PATIENTS IN UNIVERSITY OF MAIDUGURI TEACHING HOSPITAL, NORTH EASTERN NIGERIA

 
Ahmadu MS, Mubi BM, Adeyomoye AAO, Ahidjo A, Adeyinka AO, Tahir AA
Background: Carotid artery luminal diameter measurements have been used as clinico-radiological index of carotid artery atherosclerosis in patients with diabetes mellitus. Luminal diameter values have also been used in epidemiological and interventional studies as surrogate index of carotid atherosclerosis. However, values for luminal diameter measurements in diabetic patients are scarce in our environment.
Objectives: This study evaluates the carotid artery luminal diameter dimensions and degree of stenosis among adult diabetic patients using carotid duplex ultrasonography (CDUS).
Methods: This was a cross-sectional study carried out at the University of Maiduguri Teaching Hospital, Nigeria. One hundred and twenty adult diabetic patients aged 20 - 78 years had CDUS for measurements of carotid artery luminal diameter and degree of stenosis. Measurements were taken at 1cm below and 1cm above the carotid bulb for the common carotid (CCA) and internal carotid arteries (ICA). Pearson’s correlation and Student t-test were used to compare the means between the variables.
Results: There were 72 males and 48 female diabetic patients aged 20 to 78 years (mean = 50.03±11.4 years). The mean luminal diameter, in millimeters (mm), for normal (non-stenotic) carotid arteries on the right and left were (CCA=6.58±0.52 and 6.51±0.50; ICA=4.80±0.29 and 4.79±0.31); and abnormal (stenotic) were (CCA=6.41±0.62 and 6.35±0.62; ICA=3.44±0.44 and 3.11±0.29) respectively. A total of 75 patients (62.5% of study population) had no carotid artery stenosis; 38 patients (31.7%) had <50% carotid stenosis; 6 patients (5.0%) had 50-69% carotid stenosis; and 1 patient (0.8%) had 72% carotid stenosis. The prevalence of carotid stenosis in diabetic patients was 37.5% in this study. Negative and significant correlation was noted between percentage degree of stenosis and luminal diameter (r== - 0.5; p=<0.05).
Conclusion: The findings of this study have indicated the presence of atherosclerotic changes in the carotid arteries of adult diabetic patients in our environment who are at risk of developing stroke from carotid stenosis. CDUS has proved to be a valuable diagnostic and screening tool in the evaluation of these patients because of its safety, low cost, wide availability, and accuracy in detecting carotid artery disease.

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LUND-MACKAY SCORING OF INCIDENTAL PARANASAL SINUS COLLECTION ON COMPUTED TOMOGRAPHY SCAN OF HEAD AND NECK IN THE UNIVERSITY OF BENIN TEACHING HOSPITAL, NIGERIA

 

Ighodaro O. Emmanuel, Ehigiamusoe O. Festus

Background: Many a times during computed tomography scan of the head and neck, incidental density is noted in the paranasal sinuses in patients who are asymptomatic and there is need to document the degree of such opacification.
Objectives: To document the opacification and generate a numerical scoring system described as Lund Mackay Score which eases communication between the Radiologist and the referring Ear, Nose and Throat Surgeon in describing sinusitis.
Methods: This is a prospective study done in the Radiology Department of University of Benin Teaching Hospital, Benin, Edo, Nigeria. A total of 150 patients were enrolled for this study with 62% being male and 38% being females. They were patients who had cranial and neck computed tomography scans for pathologies other than that related to the sinuses.
Results: The mean age of the study population was 52.70±18.71years. Cerebro-vascular accident was the commonest indication for computed tomography scan in this study (49.3%). The total Lund Mackay Score was 0.803±2.90 for all sinuses being 0.417±1.47 for the right sinuses and 0.386±1.43 for the left sinuses. For the right, the maxillary sinus had the highest Lund Mackay Score with a value of 0.210±0.46 while the posterior ethmoidal sinus had the least Lund Mackay Score with a value of 0.027±0.16. For the left sinuses, the maxillary sinus also had the highest Lund Mackay Score value of 0.173±0.40.The posterior ethmoidal sinus also had least Lund Mackay Score value of 0.033±0.18. The Lund Mackay Score of the osteomeatal complex was 0.013±0.12 and 0.007±0.08 for the right and left respectively.
Conclusion: This study has documented the Lund Mackay score for incidental paranasal sinus
opacification as seen on computed tomography scan in our environment.

[FULL ARTICLE (PDF)]

ORIGINAL ARTICLE


 
 

MOLECULAR AND CONVENTIONAL METHODS OF DETECTING RESPIRATORY VIRUSES AMONG CHILDREN WITH LOWER RESPIRATORY TRACT INFECTION IN SOKOTO, NIGERIA

 
Shuaibu A. Hudu, Nabil S. Hamal
Background: Most infections of respiratory tract are caused by viruses but bacteria with viruses contributing to a higher proportion of infection.
Objectives: The aim of the study was to assess the epidemiology of respiratory viral infections among children less than five years of age hospitalized with acute lower respiratory tract infections (ALRTIs) at Specialist Hospital, Sokoto using conventional and molecular detection methods.
Methods: The cross-sectional study was designed to investigate the occurrence of respiratory viruses including (RSV), human Metapneumovirus (HMPV), influenza virus A and B (IFV-A and B), parainfluenza virus 1, 2, 3 and 4 (PIV 1, 2, 3 and 4), human rhinoviruses (HRV), human enterovirus (EV), human coronaviruses (HCoV) 229E and OC43, human Boca virus (HBoV) and human adenovirus (HAdV) among hospitalized children with acute lower respiratory tract infections (ALRTIs), at Specialist Hospital, Sokoto, from June 16 to December 21, 2010. The present study was also designed in part to assess the performance of the conventional methods against molecular methods.
Results: Etiologic agents were detected in 158 (95.8%) of the patients. Single virus was detected in 114 (67.9%) patients; 46 (27.9%) were co-infected with different viruses including double-virus infections in 37 (22.4%) and triple-virus infections in 9 (5.5%) ca;ses. RSV (50.3%), with predominance of group B, played a major role. Other etiological agents including HAdV, HMPV, IFV-A, PIV 1-3, HBoV, HCoVOC43 and EV were detected in 14.5, 9.6, 9.1, 4.8, 3.6, 2.4 and 1.8 percent of the samples, respectively.
Conclusion: Our results demonstrated the potential usefulness of molecular detection methods compared with conventional methods for the diagnosis of ARTIs among hospitalized children. This is the first report of HMPV, HBoV and HRV infections among hospitalized children in Sokoto.

 

[FULL ARTICLE (PDF)]

ORIGINAL ARTICLE


 
 

A TEN-YEAR REVIEW OF CHILDHOOD PATTERN OF ENDOCRINE DISORDERS SEEN IN FEDERAL TEACHING HOSPITAL GOMBE

 
Alkali YS, Adamu S, AB Ningi, A Girbo
Background: The endocrine system is a network of glands which produce hormones that regulate metabolic functions of other cells and organs. Disruption of this system results in abnormalities of growth, development and reproduction. These conditions are not rare in childhood but due to lack of diagnostic facilities, they are not looked for and are therefore under-reported. However, they should be detected early and managed promptly to avert the morbidity and possible mortality that may be associated.
Objectives: To describe the pattern of childhood endocrine diseases in Federal Teaching Hospital Gombe.
Methodology: A retrospective hospital-based study in which data were extracted from case notes of children with endocrine disorders. These case notes were traced from the registers of all paediatrics units and general out-patient departments. These case notes were subsequently reviewed and relevant data extracted and entered unto a proforma. Outcome measures as well as complications of those admitted were also noted.
Results: Ninety-four out of 14,943 paediatric cases seen were endocrine disorders giving a prevalence of 6.3/1000 with a male/female ratio of 1.5/1. Most of the cases (75%) presented before the age of ten years and Type 1 Diabetes Mellitus was the commonest disorder recorded.
Conclusion: Type 1 Diabetes Mellitus is the commonest paediatric endocrine disorder seen in Federal Teaching Hospital Gombe.

[FULL ARTICLE (PDF)]

ORIGINAL ARTICLE


 
 

EFFECT OF SUB-CHRONIC ORAL EXPERIMENTAL EXPOSURE OF MONOSODIUM GLUTAMATE ON BIOMARKERS OF HEPATIC AND RENAL FUNCTION IN MALE WISTAR RATS

 
Hassan Abdulsalam, Jamila A. Atata, Ali Waziri, Mohammed A. Chiroma, Joseph J. Gadzama, Modu B. Monguno, Sani N. Abdulazeez, Israel J. Barde
Background: Monosodium glutamate (MSG) is a food additive that acts as a preservative or as enhancer of palatability and is locally called Ajinomoto or white magi in Nigeria.
Objectives: This study assessed the effect of sub-chronic oral exposure to monosodium glutamate (MSG) on some plasma biomarkers of hepatic and renal function in adult male Wistar rats.
Methods: Sixty-four adult male Wistar rats of average weight 150 to 200 g were randomly assigned into two groups of MSG-treated and non-MSG-treated control rats (n=64). The control rats were orally given distilled water only while the MSG-treated rats were administered 5 g/kg body weight of MSG at concentration of 500 mg/ml daily throughout the period of the experiment that lasted 8 weeks; feed and water were provide to both groups ad libitum. A total of 8 rats, 4 per group were sacrificed weekly for blood sample collection and analysis of hepatic and renal biochemical indices.
Results: the result of biochemical analysis showed significant increase (P = 0.05) in mean of Alanine aminotransferase (ALT), Aspartate aminotransferase (AST), Alkaline phosphatase (ALP), Urea and Creatinine activities in the MSG-treated rats.
Conclusion: The increases in the levels of plasma biochemical parameters signal some level of alteration in the normal physiologic function of both liver and kidney.

[FULL ARTICLE (PDF)]


ORIGINAL ARTICLE


 
 

CAREER ASPIRATIONS OF MEDICAL STUDENTS AND MEDICAL INTERNS IN GHANA. IS THERE A DIFFERENCE?

 
Yifieyeh AC, Duduyemi BM, Kumahor E, Kotoku E, Moses MO, Fefemwole P, Akwetey FM
Background: Understanding the reasons for the selection of medical specialties by medical graduates is necessary for policy formulation and targeted mentoring to prevent a skewing of the lean resources and maximize the improving doctor to patient ratio in Ghana. This is particularly so due to an increase in the desire for specialization among medical graduates since the establishment of the Ghana College of Physicians and Surgeons.
Methodology: A cross-sectional study was designed. To consenting first and final year clinical students of the School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana and first and second year medical interns at Komfo Anokye Teaching Hospital and Sunyani Regional Hospital respectively were administered semi – structured questionnaires. Data were analysed with SPSS version 24 and result put in tables and graphs
Result: Three hundred and forty and 100 questionnaires were administered to students and interns with 92% and 75% responders’ rate respectively. The M: F ratio for students and interns were 1.23:1 and 1.34:1 respectively. Postgraduate specialization and additional qualification were desired by all categories irrespective of sex, financial or family consideration. Surgery (43.9% students; 33.3% interns) and Internal Medicine (23.8% students; 24% interns) were the 2 most popular choices.
Conclusion: While Surgery and Internal Medicine appeared to be the favoured choices by our students and interns, deliberate effort through mentoring is required to avert lop-sidedness in workforce in our hospitals.

[FULL ARTICLE (PDF)]


ORIGINAL ARTICLE


 
 

ANALYSIS OF BACTERIAL LOAD IN DOMESTIC WATER SOURCES IN EKPOMA, EDO STATE, NIGERIA

 
Jemikalajah, Daniel Johnson
Background: Drinking water must be free from harmful microorganisms that can cause serious ill health. Supplies of drinking water may be contaminated with sewage allowed to seep into wells or bore-holes, or faecal matter from man and animals passed into rivers, streams or pools of water.
Objectives: This study was carried out to ascertain the bacteriologic quality of domestic water sources used in Ekpoma, Edo State, Nigeria from February 2016 to June 2017.
Methods: Ten samples each of domestic water sources (sachet water, bore-holes, storage tanks, wells and river) were collected and bacteriological analysis was carried out using the total viable count and multiple tube fermentation technique to determine the most probable number of coliforms/ E. coli.
Results: The highest mean total viable count (TVC) of bacterial load of 4.1 x 106 CFU/ml was obtained for river water followed in descending order by 1.5 x 106 CFU/ml, 7.5 x 105 CFU/ml, 3.2 x 105 CFU/ml and 1.9 x 10 CFU/ml for reservoir well, reservoir tank, bore-hole and sachet water sources respectively on nutrient agar. The highest mean total viable count of bacterial load of 4.1 x 103 CFU/ml was recorded for reservoir tank followed by 1.3 x 103 CFU/ml, 3.7 x 102 CFU/ml, 3.6 x 102 CFU/ml and 0.0 CFU/ml for reservoir well, bore-hole, river water and sachet water sources respectively on macConkey agar. The highest mean of most probable number (MPN) for the presumptive total coliform counts of 140 MPN/100ml was observed for river and the lowest 0.4 MPN/100ml for sachet water. Also, the highest mean of most probable number (MPN) for faecal Escherichia coli counts of 31 MPN/100ml was obtained for reservoir well and the lowest 0.0 MPN/100ml for sachet water.
Conclusion: This study has shown that there is urgent need for an effective, thorough sanitary condition and proper purification given the bacteriological state of these water bodies in order to maintain good quality water.

[FULL ARTICLE (PDF)]

CASE REPORT


 
 

CONGENITAL CYSTIC EYE: A CLINICOPATHOLOGICAL REVIEW

 
Musa ZY, Askira BH, Zarami AB

SUMMARY
Congenital cystic eye is an extremely rare congenital anomaly that results from failure of the invagination of the primary optic vesicle between the 2mm and 7mm stage of fetal development in which the globe is replaced by a cyst. Management is multidisciplinary involving but not limited to the Ophthalmologist, Paediatrician, Radiologist, Histopathologist, an ocularist and a counsellor. Surgical intervention is usually carried out for cosmetic reasons and to confirm the diagnosis. We present the case of a seven-month female infant who presented with right orbital mass since birth and a normal left eye. She had excisional biopsy done and histology confirmed the diagnosis

[FULL ARTICLE (PDF)]

CASE REPORT


 
 

BILATERAL PROXIMAL FEMORAL FOCAL DEFICIENCY IN A NEONATE: A CASE REPORT

 
Ahmadu MS, Farate A, Farouk AG

SUMMARY
Proximal femoral focal deficiency is a rare and complex skeletal anomaly characterized by failure of normal development of the proximal femur, shortening of the lower limb, and pelvic abnormality especially the acetabulum. It was first described by Aitken in the late 1950s. It commonly occurs as a unilateral form but the bilateral variant is rare occurring in 10-15 % of cases. To the best of our knowledge, bilateral proximal femoral focal deficiency has not been reported in Nigeria. We, therefore, present this case in a 25-day-old neonate who presented to our hospital with features consistent with this complex skeletal anomaly.

[FULL ARTICLE (PDF)]

CASE REPORT


 
 

HETEROTOPIC PREGNANCIES FOLLOWING NATURAL CONCEPTION; A REVIEW OF FOUR CASES

 
Muhammad B. Aminu, Lamaran M. Dattijo, Aliyu U. Elnafaty

SUMMARY
The occurrence of spontaneous pregnancy (viable or not) in one or more sites other than the endometrial cavity at the same time is an unusual phenomenon. We aimed to draw attention to
the varied clinical manifestations and outcomes of heterotopic pregnancy (HP) amongst four consecutive patients who were managed in our facility over a two-year period. It is imperative
for all clinicians to have a high index of suspicion for HP when seeing a woman of reproductive age with suspected ectopic.

[FULL ARTICLE (PDF)]

CASE REPORT


 
 

REMOVAL OF DISTALLY MIGRATED CANNULATED INTERLOCKING TIBIAL NAIL USING SCHANZ SCREW; A CASE REPORT

 
Mamuda AA, Bello, B.

SUMMARY
Background:
Distal migration of nails is one of the reasons for nails removal, though they are hardly reported in relation to cannulated interlocking nails.
Objectives: To present a rare case of distally migrated cannulated interlocking nail of the tibia and a proposed technique for the removal of the nail using Schanz screw.
Case: A 55year old woman had cannulated interlocking nailing for diaphyseal left tibial fracture 5 years prior to presentation. She later had septic loosening of the distal locking screw with subsequent symptomatic distal migration of the nail despite united osteosynthesis. Attempt at free hand removal using conventional instruments failed due to increased distance of the nail from the entry point, malrotation and lack of visibility of the nail following obliteration by fibrous and granulation tissues within the nail cavity. Thus, an improvisation with Schanz screw, due to its threading surface was used to capture and remove the nail successfully without any cortical damage of the bone.
Conclusion: The use of Schanz screw is a safe, cheap and effective means of free hand removal of distally migrated cannulated interlocking nails.

[FULL ARTICLE (PDF)]

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vol132_jult_dec_2016

Written by Administrator. Posted in Archives

 
 

 

January - June 2016
Volume 13 | Issue 1

This journal has been online since Saturday, April 05, 2013

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ORIGINAL ARTICLES


 
 
  SERUM LIPID PROFILES AND ATHEROGENIC INDEX IN PREGNANT SAHEL GOATS: PUBLIC HEALTH IMPLICATIONS

DAUDA YAHI, NICHOLAS ADETAYO OJO, GIDEON DAUDA MSHELIA

Background: Goat meat is very popular and has a great demand all over Nigeria. However, the slaughter of pregnant goats in abattoirs and slaughter slabs for meat is becoming a serious
concern not only for future livestock population, but also for public health. Dyslipidaemia of pregnancy in meat animals may constitute threat to consumers in terms of cardiovascular risks.
Objectives: The purpose of this study was to investigate the concentrations of serum lipids at different stages of gestation in Sahel goats and to evaluate the atherogenic capacity of the lipid profile. Materials and Methods: Serum lipids profiles and atherogenic indices in pregnant and nonpregnant Sahel goats were studied. Fourteen apparently healthy adult Sahel goats comprising 12 does with mean gestation length of 148.33 ± 1.52 days and 2 bucks were used for the study. They were managed in the University of Maiduguri livestock research farm on low fat diet. Sera samples were collected biweekly for 5 months and were used for the analysis of total Cholesterol (TC), triglycerides (TG), high density lipoprotein (HDL-c), low density lipoprotein (LDL-c) and very low density lipoprotein (VLDL-c). Atherogenic indices were calculated as base 10 log (TG/HDL-c). Results: Serum TG and VLDL-c concentrations increased significantly (p < 0.05) in pregnant does compared to non-pregnant. HDL-c and LDL-c concentrations did not vary significantly (p > 0.05) between the two groups. Atherogenic indices increased progressively with advancing pregnancy compared to non-pregnant. Conclusion: It was concluded that atherogenic capacity of the lipid profile in pregnant Sahel goats is high and therefore consumption of meat from pregnant animals has high potential for atherogenic risk. Routine antemortem inspection should be conducted at abattoirs to identify pregnant animals for restriction against slaughter. Legislation prohibiting the slaughter of pregnant animals should be enforced

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ORIGINAL ARTICLES


 

PREVALENCE AND OUTCOME OF PREGNANCY AMONG ELDERLY PRIMIGRAVIDA IN AMINU KANO TEACHING HOSPITAL, KANO: A 5 YEAR REVIEW

IBRAHIM SA, JABBO MA, ATTAH AR, GARBA ID, MUHAMMAD Z.

Background: As women increasingly delay child bearing, the proportion of women having their first delivery at ''advanced maternal age'' is expected to rise. These elderly primigravidae have traditionally been considered to be at increased risk of adverse maternal and perinatal outcomes compared to their younger counterparts, because of associated pregnancy and labour complications. Objectives: To determine the prevalence of elderly primigravidae and compare their pregnancy outcome with that of younger primigravidae in Aminu Kano Teaching Hospital, Kano. Materials And Methods: This was a retrospective case control study comparing the pregnancy outcome of primigravid mothers aged 35 years and above (elderly primigravidae) with those of younger primigravidae aged 20-25 years, who delivered at Aminu Kano Teaching Hospital between January 2009 and December 2013. Results: There were 18,452 deliveries during the period under review, out of which 295 were primigravidae aged 35 years or above giving a prevalence of 1.6%. There was statistically significant higher preterm delivery rate ( X2= 10.30, P= 0.001) and caesarean delivery rate (X2= 12.15, P= 0.0001) among the elderly primigravidae compared to younger primigravidae. The elderly primigravidae were more prone to hypertensive disorders in pregnancy (X2=23.96, P=0.0001) and diabetes (X2=4.689, P=0.030) compared to the younger primigravidae. The prevalence of antepartum haemorrhage (X2=6.434, P=0.011) and uterine fibroids (X2=5.549, P=0.019) were also statistically significant among the elderly primigravidae compared to the younger primigravidae. There was no significant difference in the other maternal and foetal outcome measures. Conclusion: The prevalence of elderly primigravidae in this study was 1.6%. The prevalence of obstetric complications such as preterm delivery, antepartum haemorrhage, uterine fibroids coexisting with pregnancy and medical conditions like hypertensive disorders in pregnancy and diabetes mellitus are higher among elderly primigravidae compared to younger primigravidae. The elderly primigravidae were also more liable to have caesarean deliveries than the younger primigravidae. However there was no difference in the fetal outcome in the two groups.

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ORIGINAL ARTICLES


 
  TRADITIONAL UVULECTOMY AMONG THE NEONATES: EXPERIENCE IN A NIGERIAN TERTIARY HEALTH INSTITUTION  
ABDULLAHI M, AMUTTA SB.

Background: Traditional uvulectomy is widely practiced in some African countries with children more vulnerable to such practices, which may be associated with life threatening complications. Objectives: To determine the age at the time of the procedure, reasons and complication(s) following traditional uvulectomy. Materials And Methods: Retrospective study of hospitalized neonates presenting as emergencies following traditional uvulectomy to the accident and emergency department of the Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria, from June, 2004 to May, 2015. Results: A total of 21 cases were reviewed. Twelve(57.1%) males and 9(42.9%) were females: ratio of 1.3:1. The age ranged from 1 to 21 days with the mean age of 8.8 days. Majority 11(52.4%) of the thtraditional uvulectomies were performed before the 7 day of life. The mean duration before hospitalization was 8.4 hours. Post-uvulectomy haemorrhage 18(85.7%) was the most common complication and this was followed by septicaemia 3 (14.3%) with 2(9.5%) mortalities from the septicaemia. All the patients were anaemic. Prevention of sore throat 12(57.1%) was the main reason for traditional uvulectomy. Sixteen (76.2%) patients were lost to follow-up. Conclusion: Neonatal traditional uvulectomy was mostly done in the first week of life, prevention of sore throat was the common intent and complicated with post-uvulectomy bleeding and septicaemia. Health institutions have a role to play in public health education on the harmful effects of traditional uvulectomy.

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ORIGINAL ARTICLES


 
  SERUM ADIPONECTIN LEVELS IN PREGNANT WOMEN WITH GESTATIONAL DIABETES MELLITUS IN ZARIA, NORTH WEST NIGERIA: A CROSS SECTIONAL STUDY  

ABDULLAHI MOHAMMED, MOHAMMED MANU.

Background: Adiponectin is an adipocytokine that is exclusively produced by adipocytes with potent insulin-sensitizing property. It has been proposed to be involved in the pathogenesis of gestational diabetes mellitus, but its role is not clear; Findings from studies done across different ethnic groups are often inconsistent. Objectives: The aim of the study was to compare maternal serum adiponectin levels between Nigerian pregnant women with and without gestational diabetes mellitus. Materials And Methods: A cross sectional analytical study including one hundred and sixty nine pregnant women, 85 with gestational diabetes mellitus and 84 with normal gestation, who were evaluated between 24-28 weeks gestation. Diagnosis of gestational diabetes mellitus was made according to the WHO diagnostic criteria. Maternal serum level of adiponectin was measured and compared between pregnant women with gestational diabetes mellitus and the controls. Results: Mean maternal serum adiponectin level was significantly lower in pregnant women with gestational diabetes mellitus than in the controls (8.1 ± 1.6 vs. 10.1 ± 2.4 µg/ml, p< 0.05). When 2 2 subjects in the study groups were further categorized in to BMI < 25kg/m and BMI 25 kg/m , maternal serum adiponectin level remained significantly lower in the normal weight pregnant women with gestational diabetes compared to their BMI-matched controls (8.4 ± 1.7 vs. 11.4 ± 2.1 2µg/ml, p< 0.05). Among the overweight pregnant women (BMI 25 kg/m) on the other hand, there was no difference in maternal serum adiponectin level between pregnant women with gestational diabetes mellitus and the normal controls (7.8 ± 1.5 vs. 8.0 ± 1.1µg/ml, p> 0.05). Conclusion: It is concluded that normal weight Nigerian pregnant women with gestational diabetes mellitus in this study have lower serum adiponectin level compared to the normal weight pregnant women with normal gestation

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ORIGINAL ARTICLE


 
  SELF-REPORTED HEARING-RELATED COMPLAINTS AMONG DENTAL PROFESSIONALS: A QUESTIONNAIRE-BASED SURVEY  

ABDULAZEEZ AHMED

Background: As a result of workplace noise, dental personnel are potentially predisposed to auditory and non-auditory effects of noise which may expose hidden or imminent hearing impairment. There is the need to capture these self-reported hearing and hearing-related complaints using well designed questionnaires as a prelude to formal audiometric tests. Materials And Methods: This was a cross-sectional self-administered questionnaire study conducted between the periods April to August 2015. Participants were given questionnaires to fill and return which captured socio-demographic data and exposure to noise at workplace and symptoms experienced. Upon return of the questionnaire, each questionnaire was examined to ensure they were properly filled with signed consent. All data and findings were evaluated anonymously. Results: One hundred and thirty eight questionnaires were returned giving 86% response rate, 35(25.4%) reported hearing impairment. Eighteen (13.0%) respondents have experienced tinnitus, while 20 (14.5%) of the respondents experienced Hyperacusis, another 53(38.4%) of the respondents also have difficulty hearing in places with competing noise. Stress and sleep disturbance were also common complains. Conclusion: The presence of especially tinnitus, hyperacusis, impaired hearing in areas with competing sounds are all symptoms indicative of imminent hearing impairment that could be used to predict undetected hearing losses among dental personnel.

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ORIGINAL ARTICLE


 
  TESTICULAR AND PARATESTICULAR NON- NEOPLASTIC LESIONS IN UNIVERSITY OF MAIDUGURI TEACHING HOSPITAL: A 10-YEAR RETROSPECTIVE REVIEW  

ABBA K,TAHIR MB, DOGO HM , NGGADA HA

Objectives: The present study is undertaken to describe the spectrum of histopathological features and age distribution of non-neoplastic testicular and paratesticular lesions in the University of Maiduguri Teaching Hospital (UMTH). Materials and methods: A retrospective descriptive study of 70 testicular and paratesticular nonneoplastic lesions was conducted over a period of 10 years; between January-2005 and December2014 in the Department of Histopathology, UMTH. Histopathological examination was done after routine processing and staining with Haematoxylin and Eosin. Special stain (Ziehl-Neelsen stain) was done to confirm the presence of acid fast bacilli in cases of tuberculous epididymoorchitis. Results: There were of which
(24.3%) followed by testicular torsion and infarction (14.3%). The youngest patient was 2 years old and the oldest was 80 years of age. The highest incidence occurred in the age range of 30 – 59 years with a total of 25 cases representing 35.7%. The lowest incidence was observed in the elderly (= 60 years) with a total of 21 cases (30%). Conclusion: This study shows that inflammatory disorders are the predominant causes of the testicular and paratesticular non-neoplastic lesions capable of interfering with fertility and mimicking malignancy. There is also the need to emphasise the necessity of proper evaluation and treatment of acute orchitis and microabscess to avoid unnecessary orchidectomy.
70 cases of non-neoplastic testicular and paratesticular lesions the majority were inflammatory disorders accounting for 53 cases (75.7%). They included acute orchitis (4.3%), tuberculosis (12.9%), schistosomiasis (8.6%), hydrocoele (24.3%), chronic orchitis (10.0%), epididymal cyst (11.4%) and tumoral calcinosis (4.3%). Other categories of the lesions included congenital abnormalities (10.0%) and traumatic disorder (14.3%). Long-standing hydrocoele was the commonest lesion

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SHORT COMMUNICATION


 
  ROLE OF NATIONAL BLOOD TRANSFUSION SERVICE (NBTS) IN PROMOTING EMERGENCY OBSTETRICS CARE (EMOC)  
KULLIMA AA, KAGU MB, KAWUWA MB, BABA ZANNAH ALI, USMAN HA, BAKO BG

Background: Obstetrics haemorrhage is one of the leading cause of maternal mortality in our settings, this was compounded by the non availability to safe blood in situation of need. Hence the prompt access and availability of blood can avert this preventable cause of maternal death. Objectives: to highlight the benefits of effective collaboration with NBTS in ensuring prompt availability of blood for emergency obstetric services requiring blood for transfusion. Material And Method: All obstetrics cases requiring blood transfusion in FMC Nguru from 1st stJanuary 2006 – 31 December 2011 were retrospectively reviewed. Trends and pattern of the st strequest and source of blood were looked at within the two periods (from 1 January 2006 – 31 st stDecember 2008 and 1 January 2009 – 31 December 2011). Records of 1634 obstetric patients requiring blood transfusion or received blood transfusion in the maternity units were retrieved from the medical records, maternity ward record and blood bank. Information pertaining to their age, parity, indication for the transfusion or requests and source of blood was obtained for analysis. Data was analysed using simple percentage. st st Results: Between 1 January 2006 and 31 December 2008 only 513 (56%) of the units requested st st907 units of blood were supplied, while between 1 January 2009 and 1 December 2011 1367 ( 87%) of the 1567 units of blood requested were supplied. Within the earlier study period the only available source were from willing relatives and commercial blood donors, however between 2009 and 2011 more than 2/3 (64.2%) were supplied from the north east zonal NBTS office in Maiduguri. In 2006 through 2008, donation from relatives and commercial donors accounted for 53.22% and 46.78% respectively, but in 2009 and 2011 donation from relatives and commercial donors were recorded as 23.9% and 11.6% respectively. The commonest indication for the requests were anaemia, obstetrics haemorrhage (PPH, APH) and emergency C/S. Conclusion: Ready available source of blood will significantly improve timely availability of blood in our setting. There is the need to encourage this collaboration in other regions to ensure prompt availability of blood to attend to emergencies requiring blood transfusion.

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SHORT COMMUNICATION


 
  BONE MARROW ASPIRATION (BMA) IN ZARIA: A THREE-YEAR RETROSPECTIVE REVIEW  

AWWALU S, HASSAN A, DOGARA LG, MUSA AU, WAZIRI AD, BABADOKO AA

Background: BMA is a clinical procedure that exploits microscopy and lends itself to specialized biochemical and molecular assays for diagnosis, staging, prognostication and determining choice of therapy. Eligibility for BMA is determined following review of a patient's history, physical examination findings, Complete Blood Count and other relevant investigations. Bone marrow aspirates may be obtained from different sites of the body such as iliac crest, sternum etc. This study was to determine some patient characteristics, sites, indications and outcomes of all BMAs done between January 2002 and December 2004. It is hoped that this study will help haematologists and other physicians to understand the utility of BMA and some of its limitations. Material And Methods: It was a three-year retrospective, analytic review of all BMAs done in the stDepartment of Haematology, Ahmadu Bello University Teaching Hospital Zaria. Records from 1 stJanuary 2002 to 31 of December 2004 were retrieved, collated and analyzed using SPSS version 16. Results: A total of One hundred and thirty five (135) BMAs were done in the period under review. There was a male preponderance 77 (57.00%) with females constituting 58 (43.00%). The mean age was 31.78±20.76 years with a mode of 45 years. The minimum and maximum ages were 1 and 78 years respectively. The commonest site for BMA was the RPSIS 97(71.9%). Anaemia was the commonest indication for BMA 56(41.5%) followed by Splenomegaly 15(11.1%) and Lymphadenopathy 14(10.4%).The commonest diagnosis was combined deficiency anaemia 21(15.6%) followed by Megaloblastic anaemia 19(14.1%). Whereas 9(6.7%) were inconclusive, 14(10.4%) were normal. The complication rate was 0% and lymphadenopathy was the commonest indication that turned up with a normal BMA 5/14 (35.7%) . Conclusion: BMA is important in the evaluation of several conditions. However, there is a need to ensure proper consultation to ensure only patients that require BMA do so due to its invasive nature.

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CASE REPORT


 
  USE OF MAUERMAYER STONE PUNCH TO TREAT POSTERIOR URETHRAL DIVERTICULA CALCULUS IN A PATIENT WITH MULTIPLE CONGENITAL ANOMALIES OF URINARY TRACT  
ABUBAKAR ABDULKADIR

Background: Posterior urethral diverticulum calculus (PUD-C) is a rare urethral lesion that can pose as a diagnostic dilemma and in instances laborious to treat. Objectives: To report a rare case of posterior urethral diverticulum calculus (PUD-C) treated by the use of Mauermayer stone punch in a patient with double ureter , mal-development of the prostate and chronic viral hepatitis. Case: A 37year old male, who presented with a year history of bothersome Lower urinary tract symptoms (LUTS) with episodes of purulent urethral discharge. His posterior urethral diverticulum calculus (PUD-C) was confirmed at urethrocystoscopy alongside maldeveloped prostate, hanging verumontanum, urinary bladder trabeculations, and sacculations. He had urethrolitholapaxy using Mauermayer stone punch with a concurrent alleviation of the LUTS. Conclusion: The pertinent publications on the clinical features, treatment, and the outcome of PUDC were reviewed. Utilization of Mauermayer stone punch for PUDC urethrolitholapaxy is a novel treatment technique. It, however, alleviated the bothersome lower urinary tract symptoms and granted a satisfactory outcome in the index patient.

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CASE REPORT


 
  SPIGELIAN HERNIA: EXPERIENCE OF HOPITAL DE LA RENAISSANCE OF NDJAMENA (CHAD)  
KAIMBA BM, EDZIMBI AL, MOIFO B, PIERRE H.

Background: Spigelian hernia is an uncommon ventral hernia characterized by a defect in the semilunaris linea and is known as “hernias through the conjoint tendon”. The symptoms of Spigelian hernia are usually non-specific. CT scanning is considered the most reliable technique for diagnosis .These hernias require surgical treatment. Case: A case of Spigelian hernia was diagnosed in the patient of 56-year-old man presenting with abdominal pain associated with a reducible mass in the right iliac fossa. CT scan confirmed the diagnosis. We had performed successfully surgical treatment to repair the hernia defect. The recovery was uneventful.

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CASE REPORT


 
  MASSIVE CHRONIC BILATERAL GYNECOMASTIA IN A MIDDLE AGED MAN: A CASE REPORT  
ZAINAB MUSTAPHA, MOHAMMED A. SUWAID, MAIMUNA A. HALLIRU, SIRAJO D. YAKUBU AND ANAS ISMAIL

Gynecomastia is defined as enlargement of the male breast and derives its origin from 2 Greek words- 'gyne' and 'mastos' which mean "woman's" "breast". Gynecomastia is a clinical condition and often has three radiological patterns which are nodular, dendritic and diffuse glandular patterns. We report a case of a 42 year old man of Hausa-Fulani descent with massive bilateral breast enlargement of multifactorial origin. Investigations done included thyroid function test, liver function test and additional basic blood workup. A mammogram was done, which was followed by breasts ultrasound. Additional radiological imaging included abdominal and testicular sonograms and diagnosis of massive bilateral gynecomastia was made. Anti-psychotics are a documented cause of gynecomastia while thyroid dysfunction is an often overlooked etiology of male breast enlargement. Medical treatment may address the underlying pathology in some cases; however, surgical reconstruction must be considered in severe, chronic cases as it addresses the physical deformity which is a significant cause of depression in these patients. The role of radiology in excluding the causes of gynecomastia cannot be overemphasized and is pertinent in the management of this condition.

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CASE REPORT


 
  GIANT CELL TUMOUR OF THE FIRST METACARPAL - REVIEW OF LITERATURE  
LAWAL SULEIMAN, CHOM NUHU DUNG1, IGASHI JOSEPH BAKO, DAHIRU ISMAIL LAWAL IBRAHIM MUHAMMAD ZARIA

A case of giant cell tumour of the first metacarpal has been presented, its radiological features discussed and literature reviewed

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CASE REPORT


 
  ELLIS-van CREVELD SYNDROME IN A NIGERIAN WOMAN: A CASE STUDY  
AHMADU MS, TALLE MA, AHIDJO A, TAHIR AA

Ellis-van Creveld (EVC) syndrome or chondroectodermal dysplasia is a rare, autosomal recessive thdisorder that was first described by Ellis and van Creveld in the mid-20 century.The syndrome is characterized by a tetrad of chondrodystrophy, post axial polydactyly, and hidrotic ectodermal dysplasia, mostly involving teeth and nails and a high frequency of congenital cardiac anomalies, most frequently a common atrium.There has been no documented case report of EVC syndrome from Nigeria in the literature. We, therefore, present a 30 year-old Nigerian woman who presented to our hospital with features consistent with this rare syndrome.

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CASE REPORT


 
  CHRONIC MYELOID LEUKAEMIA PRESENTING WITH MASSIVE ASCITES: A CASE REPORT  
YUGUDA SALEH, GIREI I. AHMED, SAIDU ABUBAKAR, LAWAN I. ALIYU

Chronic Myelogenous Leukemia (CML) is a clonal disorder of the pluripotential stem cell characterized by anaemia, extreme blood granulocytosis and granulocytic immaturity, basophilia, often thrombocytosis, and splenomegaly.Only a few cases of extramedullary manifestation have so far been reported in CML. Wepresent a case of CML in accelerated phase with massive ascites who responded well to combination chemotherapy and oral hydroxyurea.

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july-dec-2014

Written by Administrator. Posted in Archives

 
 

 

July - December 2014
Volume 11 | Issue 2

Online since Saturday, April 05, 2013

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ORIGINAL ARTICLES


 
 
  DISTRIBUTION OF ABO, Rh D BLOOD GROUPS AND HAEMOGLOBIN PHENOTYPES AMONG ANTENATAL CLINIC ATTENDEES IN FEDERAL MEDICAL CENTRE NGURU, NIGERIA

1BABADOKO AA, TAKAI IU, KAWUWA MB

Background: Blood groups antigens and haemoglobin genotypes are genetically controlled and are specific to an individual. Blood groups remain unchanged throughout life and are important to avoid fatal blood transfusion reactions. Haemoglobin phenotypes are necessary for the laboratory detection of most common clinically important haemoglobin variants as it determines the transfusion demand which is necessary for setting up and planning of a blood transfusion unit. Objectives: To determine the distribution of ABO, Rh D blood groups and haemoglobin phenotypes in pregnant women attending antenatal care at the Federal Medical Centre (FMC) Nguru, Yobe state, North-Eastern Nigeria. Methods: A retrospective chart analysis of 5,519 records of pregnant women who were sequentially booked in antenatal care clinic at the permanent site of FMC Nguru, over a 2 year period, from January 2009 to December 2010. The ABO and Rh D blood groups and haemoglobin electrophoretic pattern were obtained from the haematology antenatal record register and analyzed. Results: Overall, a total of 5474 and 5508 records were analyzed for ABO/Rh D blood groups and haemoglobin electrophoretic pattern respectively. The mean age of the study subjects was 24.6 ± 5.84 years and a mean packed cell volume of 32.6 ±4.51%. Blood group O was commonest accounting for 49.2% followed by blood group B (26.0%) and A (21.3%) while blood group AB had the lowest distribution of 3.5% (O>B>A>AB). Rhesus Rh D positivity (RhD/RhDd) rate was 95.4% while RhD negativity (Rhdd) accounted for 4.6%. Five haemoglobin phenotypes (electrophoretic pattern) were recorded in the order of HbAA (76.12%) > HbAS (23.4%) > HbAC (0.27%) > HbSS (0.16%) > HbSC (0.05%). HbAA and HbAS occurred more frequently than other haemoglobin variants. Conclusion: Although our study included only pregnant women, the finding of this study is consistent with the previously published data in Nigeria. This study will serve as a baseline data for FMC Nguru to determine and formulate an effective and efficient blood transfusion services amongst pregnant women and also it will serve as a guide for premarital counselling in this community.

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ORIGINAL ARTICLES


 

DETERMINATION OF GROWTH HORMONE, TESTOSTERONE AND ESTRADIOL IN CORD BLOOD AT THE UNIVERSITY OF MAIDUGURI TEACHING HOSPITAL

GALI RM, UDOH AE, USORO CAO, CHAMA CM, BASSEY IE, MAMZA YP

Background: Cord blood provides data on problems of neonates including factors that may serve as indicators of future disorders. Objectives: To determine the values of growth hormone, testosterone and estradiol using cord blood. Methods: Cross-sectional study using Cord blood of babies born in the labour ward of the University of Maiduguri Teaching Hospital (UMTH) Borno State, Nigeria. The samples were analyzed in the Department of Medical Laboratory Science, Chemical Pathology Unit, University of Calabar, Nigeria. Enzyme- linked immunosorbent assay (ELISA) specific for the analysis of growth hormone, testosterone and estradiol was used. Results: Two hundred and eighty nine babies comprising 152 (52.8%) males and 137 (47.2%) females cord blood were analyzed. Nineteen were preterm and 270 were full term babies. The mean serum levels of estradiol and testosterone in both male and female babies were similar (2.47±0.31ng/ml male, 2.54±0.29ng/ml female and 1.73±0.60ng/ml male, 1.62± 0.64ng/ml female) respectively. The mean serum level of growth hormone in male was higher than that of female but not statistically significant (50.92±34.42ng/ml male and 45.95±30.87ng/ml). Conclusion: Cord blood Growth Hormone, testosterone and estradiol of male and female babies do not differ significantly at birth.

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ORIGINAL ARTICLES


 
  BARRIERS TO UTILIZATION OF EYE CARE SERVICES IN RURAL COMMUNITIES IN EDO STATE, NIGERIA  

EBEIGBE JA, OVENSERI-OGBOMO GO

Background: Visual impairment and blindness due to ocular diseases are significant public health problems in developing countries, including Nigeria. Evidence suggests that poor uptake
of available eye care services by potential beneficiaries is a major barrier to attaining universal access to eye care services. Objectives: To determine the factors that prevents utilization of eye care services in rural communities. Methods: This was a cross- sectional community based survey. Three rural communities in three different Local Government Areas- Obe, Evboneka and Orior of Edo State were selected by convenient sampling. One hundred subjects were selected by systematic random sampling from each of the three villages visited. This made a sample size of 300. There were 132 (44%) males and 168 (56%) females. The age range was between 40 to 75 years, with a mean age of 55.2 ± 2.1 years. Results: The barriers identified were felt need for eye care services (33.3%), cost of treatment (26.7%), the need for escort (8.3%). and social engagement/belief (8.3%). Sixty-eight per cent of the sample population had never had their eyes examined in a hospital before. Of the thirty-two per cent of those who had gone to the hospital for eye care services, 21% were females. This resulted in a statistically significant difference in gender utilization of eye care services ( p<0.0001). There was also a significant association between the level of education and health care seeking behaviour of the sample population (p = 0.008). Conclusion: The findings of this study suggest that ignorance, poverty and gender are major barriers to utilization of eye care services by communities. Health promotion programmes need to incorporate community based health education and explore ways of making eye care services affordable in rural areas. Also, enlightenment programmes and workshops targeted at men should be carried out to educate and encourage better eye care seeking behaviour among them.

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ORIGINAL ARTICLES


 
  TUBERCULIN SKIN TEST AND SERUM ALBUMIN AMONG SPUTUM SMEAR POSITIVE PULMONARY TUBERCULOSIS PATIENTS IN MAIDUGURI, NIGERIA  

GWALABE SA, YUSUPH H, MUSTAPHA SK, IGE OM, GONI BW, BAKKI B, TAHIR A

Background:tuberculin, a Purified Protein Derivative (PPD), is introduced into intradermal tissues using a small-gauge needle. The amount of induration is measured in mm after 48-72 hours. In the setting of malnutrition, DTH responses are markedly depressed. 8 The significance of these effects depends on previous nutritional status of the individual, and the nature and duration of infection. 9 Malnutrition is observed frequently in patients with PTB 10 and it has a profound effect on cellular immune function. It is an important risk factor for TB, given that CMI is the key host defence against TB. The aim of the study was to determine the relationship between the intensity of Mantoux responses and serum albumin in HIV-negative sputum smear positive PTB patients in Maiduguri, Borno State, Nigeria

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ORIGINAL ARTICLES


 
  TRADITIONAL MENTAL HEALTH PRACTITIONERS IN GOMBE: KNOWLEDGE, ATTITUDE AND PRACTICE  

YERIMA MM, WAKIL MA, IBRAHIM AW

Background: There are many studies on the knowledge of, attitude towards and practices of mental health workers towards mental illness in Nigeria. However, there are few studies on the knowledge of, attitude towards and practices of traditional mental health practitioners towards mental illness. Objectives: The present study investigated the knowledge of, attitude and practices of traditional mental health practitioners towards mental illness. Methods: We recruited four traditional mental health practitioners (in a traditional mental healing house) into
the study, and used focus-group discussion to explore the knowledge of, attitude towards and practices of traditional mental health practitioners in Gombe, Nigeria. Results: All the
participants were married Muslims, aged between 39 and 53 years (mean age of 47 years). They attributed the causes of mental illness to Aljannu (evil spirit/demons), febrile illness and
disorientation. Sleep deprivation and “increased power of the blood” were the mechanisms for the causation of mental illness. Conclusion: Traditional healers in Gombe treat most of the
patients with mental illness, despite their poor knowledge of the causes and principles of treatment of mental disorders. This calls for increased public awareness of mental illness

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ORIGINAL ARTICLES


 
  HISTOLOGICAL OUTCOME OF BIRADS 5 BREAST LESIONS IN MAIDUGURI, NORTH EASTERN NIGERIA  

MUSTAPHA Z, ABUBAKAR A, MODU AA, PINDIGA UH, OKEDAYO M, ANNONGU IT

Background: BIRADS 5 breast lesions are greater than 95% suggestive of malignancy according to the ACR-BIRADS lexicon. Objectives: To review histological outcome, positive predictive values, and specificity of BIRADS category 5 breast lesions. Methods: This retrospective study reviewed all the demographic and histopathologic results of patients with BIRADS 5 breast lesions diagnosed in university of Maiduguri teaching hospital, North Eastern Nigeria over a period of one year with their 2 year follow-up mammogram. Results: Twenty three patients, aged 17 – 60 years, with mean age of 40+ 10.1 years were diagnosed with BIRADS 5 breast lesion during the study period. The lesions were bilateral in one (4.3 %), on the right side in 9 (39.1 %) and on the left side in 13 (56.5%) patients. Nineteen (82.6%) had malignant lesions, with invasive ductal carcinoma being the commonest malignancy (69.6%) and fibroadenosis was the commonest benign lesion 2 (8.7 %). The specificity and Positive Predictive Value were 50% and 82.6% respectively. Conclusion: The cancer rate in our study is about 82.6 % which is lower than the BIRADS lexicon of 95%, therefore we recommend a detailed verification of the BIRADs categorisation in our environment.

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ORIGINAL ARTICLES


 
  USEFULNESS OF NITRITE TEST IN SCREENING FOR URINARY TRACT INFECTION IN CHILDREN WITH SICKLE CELL ANAEMIA  

YAUBA MS, AIKHIONBARE HA, OGUNRINDE GO, BUGAJE MA

Background: Screening for urinary tract infection (UTI) among children with SCA can lead to early detection of UTI in childhood. This may necessitate further evaluation and early effective interventions with reduction in the number of individuals who develop end-stage renal disease (ESRD). Objectives: To evaluate the usefulness of nitrite test in screening for UTI in children with SCA. Methods: Two hundred and seventy two children with SCA both in steady state and in crisis (anaemic and vaso-oclusive), aged 6 months to 15 years were screened for significant bacteriuria. The study was conducted over a period of 8 months (February to September, 2012). Urine samples were aseptically collected and incubated aerobically at 37°C for 24 hours. The study was conducted in the paediatric medical ward, emergency paediatric unit and institute of child health, Banzazzau all of the Department of Paediatrics, Ahmadu Bello University Teaching Hospital, Zaria. Children whose urine samples yielded =105cfu/ ml of urine on two consecutive cultures were regarded as having significant bacteriuria. Results: Bacterial isolates were detected in 22 (8.1%) of the 272 subjects with SCA. Of the 272 children with SCA, 66 (24.3) had positive nitrite test. The nitrite test has the sensitivity, specificity and positive and negative predictive values of 68.2%, 79.6% and 22.7% and 96.6% respectively. Conclusion: Nitrite test is not a useful screening tool for the diagnosis of UTI in SCA children..

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ORIGINAL ARTICLES


 
  AN APPRAISAL OF MALE MAMMOGRAPHY IN MAIDUGURI, NORTH EASTERN NIGERIA  

MUSTAPHA Z , MINOZA K , OKEDAYO M , ABBA ALI A , NGGADA HA , KYARI M

Background: Male breast diseases are uncommon and male breast cancer is rare, constituting about 1% of breast cancers seen worldwide. Previous studies have shown that gynecomastia and carcinoma are the commonest conditions affecting the male breast, with increasing incidence of both in recent years. Imaging studies of male breast diseases constitute only about 1% of overall breast imaging in most centres. Objectives: To determine and document the pattern of male breast diseases seen in the mammography unit of Department of Radiology, University of Maiduguri Teaching Hospital. Methods: A retrospective study of all male patients with complaints of breast swelling referred for imaging at the department of Radiology, University of Maiduguri Teaching Hospital over a six year period from September 2007 to December 2013. The medical records, imaging and biopsy results were reviewed. Results: Ten male patients were referred for breast imaging, ranging in age from 14 to 58 years with mean age of 31.3 + 13 years. Nine (90%) had gynecomastia, of which five were histologically-proven, and one had acute mastitis. Carcinoma was not diagnosed in any of these patients. The left breast was affected in 80% of cases. Conclusion: Gynecomastia is the commonest male breast lesion in our environment. Awareness of the usefulness of imaging studies of male breast lesions needs to be encouraged..

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CASE REPORT


 
  CUTANEOUS BRONCHOGENIC CYST: A RARE PRESENTATION AS ANTERIOR CHEST WALL CYSTIC MASS  

PINDIGA UH, ABDULLAHI YM, 1ADOGU IO, SULEIMAN IE

SUMMARY:Bronchogenic cysts are uncommon and occur along the trachea-bronchial tree, lungs and mediastinum and even more uncommon in the skin tracheo-bronchial tree especially the anterior chest wall. It is a congenital abnormality that arises as a result of abnormal budding along the foregut in early embryogenesis. The diagnosis is usually missed clinically and majority of the cases are histologically diagnosed. The diagnosis in our case was histologically made and revealed a fibromuscular cyst wall lined by pseudostratified ciliated columnar epithelium with few goblet cells and sub-epithelial mucinous glands. We report a case of cutaneous bronchogenic cyst that occurred in the skin of the anterior chest wall over the manibrium sterni.

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CASE REPORT


 
  PENILE ECTOPIC TESTIS: A CASE REPORT  

IBRAHIM AG, ALIYU S, ADAMU S, SALIM MU

SUMMARY Cryptoorchidism or undescended testis is the most common congenital genitourinary disorder in boys. The true undescended testis has stopped along the path way of normal descent, while ectopic testis is in an aberrant location, such as the base of the penis, superficial inguinal pouch, medial aspect of the upper thigh, or the contra lateral scrotal sac. The undescended or ectopic are both referred to as maldescended testis. We report a case of a 30 months old child with ectopic right testis at the dorsum of the base of the penis who was managed by orchidopexy

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LEFT VENTRICULAR GEOMETRY IN UNTREATED HYPERTENSIVE PATIENTS PRESENTING TO A TERTIARY HOSPITAL IN NORTH EASTERN NIGERIA

Written by MA TALLE, BN OKEAHIAL, B BAKKI, CO ANJORIN, MM BABA, BW GONI, H YUSUF. Posted in Archives

Abstract Background: With the increasing prevalence of hypertension, an increase in burden of diseases due to hypertensive changes in left ventricular (LV) geometry is eminent. Assessment of LV geometric pattern identifies hypertensive patients with increased risk of cardiovascular mortality and morbidity.Methods: This was a cross-sectional study in which LV geometric patterns were evaluated in treatment naïve adult hypertensive patients. Blood pressure (BP) and anthropometric parameters were determined using standard protocols. Echocardiographic LV indices were obtained using American Society of Echocardiography (ASE) guidelines. Spot urine sample was collected for determination of urine albumin-creatinine ratio(ACR). Data was analyzed using SPSS Version 16 for windows and a p value of =0.05 considered significant.Results: One hundred and thirty six patients (made of 66 males and 70 females) with a mean of 44.82 (10.51) years were studied.Abnormal LV geometry was observed in 80.88%. Concentric remodeling was seen in 44.12%. Concentric left ventricular hypertrophy (LVH) was present in 24.26% while 12.50% had eccentric LVH, giving an overall prevalence of 36.77% for LVH.LVH is commoner among the obese and those with stage II hypertension. Ejection fraction (EF) and fractional shortening(FS) were significantly lower in eccentric hypertrophy but did not differ in other geometric patterns. Systolic blood pressure, pulse rate and ACR independently predicts LVH.Conclusions: There is a high prevalence of abnormal LV geometry and LVH in newly presenting untreated hypertensive patients. Eccentric hypertrophy is associated with lower systolic function compared to other geometric patterns.

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Written by Administrator On Sunday, 24 March 2013 17:23

Professor Mohammed Bukar

EDITOR-IN-CHIEF, BORNO MEDICAL JOURNAL

DEPARTMENT OF OBSTETRICS AND GYNAECOLOGY
UNIVERSITY OF MAIDUGURI TEACHING HOSPITAL P.M.B
1414 MAIDUGURI, BORNO STATE, NIGERIA
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DR ALIYU M. KODIYA

ASSISTANT EDITOR-IN-CHIEF, BORNO MEDICAL JOURNAL

UNIVERSITY OF MAIDUGURI TEACHING HOSPITAL P.M.B
1414 MAIDUGURI, BORNO STATE, NIGERIA
TEL:08036289875
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

NMA BORNO STATE CHAPTER

Chairman: Dr. Aliyu Mohammed Kodiya


Vice Chairman: Dr. Mohammed Ali Ramat

Secretary: Dr. Yakubu M. El-Yakub


Assistant Secretary: Dr. Abdulhakeem M. Ngulde


Treasurer: Dr. Aliu A. Usman


Financial Secretary: Dr. Mohammed Y. Mahmood


PRO: Dr. Aminu A. Aji


Editor-in-Chief: Prof. Mohammed Bukar


Ex-Officio I: Dr. Mohammed Baba Shehu


Ex-Officio II: Dr. Kumshe Mohammed Abba

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Chairman: Dr. Adamu Sadiq Abubakar

Vice-Chairman: Dr. Abubakar A. Kullima

Secretary: Dr. Hassan Mohammed Dogo

Assist Secretary: Dr. Farouk A. Garba

Treasurer: Dr. Zainab Yero Musa

PRO: Dr. Zara Wudiri

Editor-in-Chief: Prof. Mohammed Bukar

Ex-Officio I: Dr. Aliyu Mohammed Kodiya

Ex-Officio II: Dr. Sanusi M. Ibrahim

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